108 cases of dogs infected Chinese and Western combined treatment – pug forum – China Animal Husbandry Website – A useful animal husbandry website

Chinese and Western binding of 108 dogs infected http://www.atcvm.cn Pet Garden

Chen Yuku 1, Xing Yudai 1, Song Xudong 2, Hu Yao 2, Song Daru 2
1. Jiangsu Animal Husbandry and Veterinary Vocational and Technical College, 225300; 2. Nanjing Master Animal Science and Technology Research Institute Pet Clinic, 210095, 210095)

Dog small viral infection is an acute, thermal infectious disease caused by dog ​​fine viruses , Clinically characterized by hemorrhagic enteritis or non-hydrazine myocarditis [1]. Dogs in different ages, genders, and varieties can infection, high mortality, is one of the main diseases that endanger the dog industry. From January 1, 2006 to October 30, 2006, the Pet Clinic Pet Clinic of Nanjing Master Announcement was 108 cases of dog-free virus infection. After the treatment of Chinese and Western combined, 79 cases were cured, 73.1% cure rate was 73.1%. . Now combined with the treatment process of typical cases, talk about our therapeutic experience.
1 108 cases of dog-like viral infection

Variety and age

variety
(only)
Activity age (month)
2
3
4
5
6
7 ~ 12
13 ~ 24
25 ~ 36

7
1
1

1
1

1

Tibetan Mastiff
6

Bagend Dog
1

1

Pomeranian
6

1

German Shepherd
11

4
2

VIP
8

1
1
2
1
1

Shami
1

1

1

2

1

Cocardial dog
5

1

Bear dog
1

1

Beijing Bar Dog
3
1
2

Schnauzer
6

3

5

1
2

1

1
1

Hound
2

1
1

Big White Bear
1
1

Yorkshire
2

1

1

Labrador dog
2

1

1

1

Alaska
4

Samoyed Dog
2

1
1

Gaodian dog
1

1

1

1

Hybrid
18
2
5
5
1
1

108
6
35
18
15
12
5
12
4
1

13.9
13.9
32.4
16.7
13.9
11.1
4.7
11.1
3.7
0.9

As seen from Table 1, 108 dogs in dumptrophils infected infertile dogs, with Herbs, Alaska and Samoyed and other foreign varieties, there are Chinese varieties such as Tibetan Mastiff, Beijing Bar, and have not pure Bulls, a total of 28 varieties, covering most of the dogs of Nanjing pet dog, indicating that dog fine virus infection is not divided into any variety; from the percentage of the epistemology of the disease, because of the protection of maternal antibodies The incidence of dogs under 1 consecutive age is 2 months; the incidence is 2 months, followed by 3 months and 4 months, during which time the maternal antibody level is low, and the poodle body is tender, and the immune organ development is not perfect. , Specificity and non-specific immune function is not perfect, and many stress factors such as milk, feeding environment changes, the incidence rate is increased [2]. The percentage of sick dogs in 1 year old began to decline, indicating that the body’s immune organ function gradually improved, although the disease, but the condition was gradually increased.

From the onset month, the disease can occur, but the highest incidence in October and March. Since January, the case gradually increased, and the peak reached in March, 17.6%, then gradually decreased, decreased to the lowest point in July, and the incidence rate was 0. Since August, the incidence has gradually increased, until October has reached the second peak, 22.2%; from mortality, the highest is October, 6.5%, followed by April, 5.6 %, The lowest is July, the mortality is 0. Note that the most serious months of dog fine virus infections are from 3 to April and October. See Table 2.
Table 2, on January 1, 2006, on September 30, 2006, China, China

Month
Category
January
March
April
May
June
July
August
September
October

Different months (only)
9
13
10
12
2
4
8
24

7.5
17.6
12
9.3
11.1
1.9
3.7
7.4
22.2

2
2
2
6
4
3
0
2

1.9
1.9
1.9
5.6
3.7
2.8
0
1.9

2 Treatment
Factors affecting dog fine virus infection rates and dogs, age, physique, mother origin Antibody level, immunojection, and season, etc. The combination of Chinese and Western combination has achieved a more satisfactory results.

2.1 antibacterial and anti-inflammatory, prevent secondary infection
antibacterial and anti-inflammatory preferences of ampicillin sodium 0.5 g to 5 g, diluted with physiological saline 100 to 250 mL, with a pretty skin test, subcutaneous injection or intravenous drip. It is also possible to use malicin, gentamicin, helix maternal or sulfonamide. Metronidazole prevents a lot of anaerobic bacteria caused by intestinal intestines, promoting the healing of the impeded mucosa, and is therefore commonly used to control anaerobic infection.
2.2 Mechanical, corrective water and electrolyte imbalance

usually use the Ringer’s liquid with a 5% glucose solution, a proportion of 1: 1 to 2. About the calculation of the amount of liquid should be construed from the following three aspects: First, the dayIt is required, that is, the basic demand of the per day, the adult dog is 66ml / kg body weight; the second is the loss of the loss on the day, that is, vomiting, diarrhea; the third is lost, generally, mild dehydration fluid has lost With a 4% weight, moderate dehydration accounted for 6%, and severe dehydration accounted for 8%. It can also be calculated by determining the red blood cell compressive capacity (PCV), which has been lost, and the formula has been calculated as follows:
=
W
×
BVL
([[
1

HT
)
HT1

where x is lost; W is body weight; BVL is normal blood volume accounting for weight Percentage (7%); HT is normal PCV; HT1 is pathological PCV. The amount should be filled with the amount of liquid = lost amount + the day required amount + the day loss amount
The amount of hydraulic fluid calculated by the above method is not very accurate, so, – first with the calculated amount of L / 3 ~ 1/2, then then Revised the amount of liquid according to the rehydration effect [3].

Dorsable dogs with vomiting, pay attention to potassium, severe diarrhea, should pay attention to supplementate sodium bicarbonate solutions. Because the main manifestations of dog fine viral gastroenteritis are vomiting and diarrhea, in order to ensure the energy supply of the body, 25% glucose solution, energy-mixture, and the like can also be selected. At the same time, pay attention to calcium, to enhance myocardial shrinkage, causing bruises, and reduces bleeding. Calcium is usually used with calcium gluconate injection, intravenous infusion, or injecting a deep portion injection; supplementation with a 10% potassium chloride solution, add 5% glucose solution, slow intravenous infusion. Intravenous drip dog blood albumin, which is conducive to the rapid recovery of body osmotic pressure and body fluid balance.

2.3 Medium and viruses
The early days of dog fine virus infection can be used to use anti-dog fine viruses to avoid serum, the amount is 0.5 ~ 1.5ml per kilogram of body weight, subcutaneous or muscle injection, it is best to choose In the heaven, large vertebra, the cylinder injection, for 2 to 3 days. Or use the rehabilitation dog infected with dog fine virus, 3 to 5 ml per kilogram of body weight, blood transfusion; early use of dog fine virus monoclonal antibody, muscle injection or in the heavens, body columns, and Hundreds of club injection, good effect.
2.4 Enhanced immunity
Left imidazole injection 10mg per kilogram of body weight,Subcutaneous injection or posterior hole injection, 1 hour, there is a double-dimensional power of immunity and insectitis; the interferon is 10 to 200,000 units, subcutaneous injection, or injected in the Baihui, after three miles, grab the wind, every 2 1 time, directly inhibiting viruses and enhances body immune function; thymosin 2mg, subcutaneous injection or Sanjiao Yu, post-three miles, 1 time, to enhance cellular immune function; Astragalus polysaccharide injection 2 ~ 10ml, subcutaneous injection, Each 24 hours can improve the body specificity and non-specific immune function.

2.5 symptomatic treatment
2.5.1 Throttle and hemostasis? The stop spit can be used vitamin B6, Ai Mao, stomach resisted, three miles, intestinal abdominal pain, hydrochloride Base (654-2), subcutaneous injection or intravenous drip. If vomiting is blood, it is compatible with Renitz, 2 to 5 mg per kilogram of body weight, intravenous drip, 1 hour every 24 hours.
Hemodemics use hemostasis per kilogram of body weight 10mg, intravenous drip, 1 hour every 24 hours; methylene 1 mg per kilogram of body weight, intravenous drip, 1 hour per 24 hours; vitamin K1 10 mg, subcutaneous injection. Or apply vitamin K3, aid blood, and the like.
2.5.2 anti-shock? Shock symptoms can be significantly available to 5 ~ 15mg, muscle injection.
2.5.3 Clean the gastrointestinal, protect the gastrointestinal mucosa
Oral Smecta, such as Smecta, etc., can protect the inflammatory gastrointestinal mucosa. When the blood is discharged, the intestinal feces and blood stasis are cleaned with 0.1% potassium permanganate temperature solution to reduce the growth of bacterial growth and prevent toxins from absorption. Just pull, use the dysenger (子, tulip, slanggen root, hawthorn, rhubarb, son, ubiquitous, half-summer, licorice) with 80,000 units, and vomiting and pulling the stopper Changed to vomiting (ubophils, blister, land, whitehead, half-summer, tangerine peel, medlar) 30ml, warm water diluted 100 ~ 200ml slow rectal drop, even rectum reservations. The severe bleeding can be added to the vitamin K3, Yunnan Baiyao powder, etc., as appropriate.
2.6 Strengthening Nursing
“Three points for treatment, seven-point care”. During diarrhea, it is necessary to ban, and water to reduce gastrointestinal burden. During fasting, we can use full nutrient venous. The disease should pay attention to keep warm, except for treatment, minimize stress. Recovery periods to control diet, delicious tonic salts or feed a small amount of low-fat digestible foodThe substance is gradually transitioned to normal food.
2.7 Mid-Veterinary Diseasement Theory
2.7.1 Dog fine virus infection is a bloody in the mid-veterinary medical certificate [4, 5]. Chinese veterinary medicine believes that blood dishes are epidemics to invade gastrointestinal tract, which blocked the blood, and chemically brought to pus and blood. The blood-blood passengers are more than the fire, and the fire is forced to rush. Therefore, the early should be cleverly detoxified, and the cold blood stop is treated. Take 20g, Huanglian, Palm, 15g, Yam, List, 10g of Yam, Licorice; 15g of blood weight, 加 加 加 地, 冬 20g; 10g Dramatic vomiting, plus bamboo rush 15g; loss of appetite plus 30g; blood loss, plus jaundice 30g, Angelica 15g; 眵 眵 难 者 加 菊 花 20g, Qin Peel 10g. Shuijianbi, 50 ~ 100ml each time, 3 to 4 times a day, 1 dose per day, puppies, discretion [6].
The middle and late stage of qi and blood circulation, the blood circulation and blood stasis are treated. Take Balance 15g, Honeysuckle 10g, Shuihua 10g, Diuri 10g, Codonopsis 10g, Atractylodes 6g, Angelica 10g, Ejiao 6g, Licorice 10g, Water Juice, 50 ~ L00ml each time [7 ].
2.7.2 Acupuncture therapy? Acupuncture therapy, especially water needle injection, has a good effect on the disease. White needle therapy is available in San Jiao Yu, Dachangshu, Spleen, Xiao Yu, Guan Yuanshu, Houhai, Handan, Sanzhao, etc .; water needle therapy can be selected after the sea, spleen, after Sanli points. For disease dogs with low body temperature, feasible, spleen, San Jiao Yu and other ophthalmuses [8].
3 Typical cases
January 22, 2006, a 53-day German male shepherd dog, with a weight 4.5kg. Sign in, the dog is airborne from Fuzhou to Nanjing from January 21, and immunization is unknown. The dog shower is given to the dog. The next morning, it feeds milk, dog food, ham sausage. There are 4 times in the afternoon, and the feces is thin, and the spirit is irritated. Clinical examination, there is a small amount of eyelid, snot, body temperature 39.2 ° C. The test strip is used for quick diagnosis test strips with South Korea, and the dog is hot is negative, and the dog is positive for a small virus. The following medication was treated on the same day.
Linde’s liquid and 5% glucose biomaric saline (proportion of 1: 2, the same below) 100ml, vitamin C 1G, Vitamin B6 1G, intravenous drip; Linger’s liquid and 5% glucose physiological saline 100ml, stop bleeding 2ml, aminolic acid 1.5mL, hydrochloride 5mg, intravenous drip; dog fine virus monoclonal antibody 5ml, 100 Acupoint injection; 0.9 ml of leftimidazole, subcutaneous injection; 1 ml of sodium normomycin, rear pocket injection.
On January 23, the complaint, after returning to 3 times yesterday, pulling 2 times of stinking feas. Clinical examination, body temperature 39 ° C. Diarrhea occurs during measuring temperature, diarrhea water sample, and there is a small amount of blood. Treatment: Linde’s fluid and 5% glucose physiological saline 250ml, vitamin C 1G, vitamin B6 0.2g, stopped blood sensitivity 2ml, intravenous drip; full nutrient solution 100ml, intravenous drip; Linger Six 100ml, methylene 1 ml, hydrochloric acid, intravenous carine , Backpoint injection; traditional Chinese medicine flat stomach (atractylodes, mount, forsythia, scorpion, hawthorn, tangerine, ubiquity, tulip, licorice) 250ml, and retain the enema after heating to 38 ° C.
One morning diarrhea on January 24, the feces were dark brown, the body temperature was 38.1 ° C, the spirit is slightly. Treatment: Except for the above drug, 0.5 g of ampicillin, subcutaneous injection, 1 hour.
On January 25, the main contraction, pulling, blood, vomiting out of white mucus last night last night. Clinical examination, body temperature 38.9 ° C, dry nose dry, poor spirit. Treatment: 10% calcium gluconate injection 4mL, 10% potassium chloride is 2 mL, and 250 ml of the Chinese medicine flat stomach fluid is continued to retain the enema. The remaining drugs are the same as before.
On January 26, the body temperature was 39.9 ° C, and the gods were sluggish. The vomit is a white mucus, and the number of diarrhea has increased and a large red blood is discharged. Treatment: In intravenous drip drugs, increased canine blood albumin 5ml to enhance immunity; anti-virus-free viruses high from serum 5ml, large vertebrae and body colloidal skin, neutralized viruses. Other therapeutic drugs and methods are the same as before.
On January 27, I spit once in the morning, the body temperature was 38.9 ° C, but the blood was several times. Treatment methods and drugs on January 26.
January 28th,The main contraplane, lost 4 to 5 times yesterday, feces with blood, but no vomiting. Clinical examination, body temperature 38.5 ° C, urine specific weight 1.025, urine pH5, urinary ferrin “+”, urinary metallic “++”, urine glucose “++”. Treatment: Dog cat special anti-Poluster 1, oral administration, 1 ml every 24 hours; 1ml, oral, 1 hour every 6 hours; 1.5ml, oral, 1 hour every 6 hours; Fule B 1ml, Oral, 1m of blood, 1ml, oral, oral, 1 hour every 6 hours; 0.9% sodium chloride injection 100ml, 5% sodium hydrogencarbonate injection 10ml, intravenous drip; full nutrient solution 100ml, venous drop Note; Lin Gelle fluid and 5% glucose physiological saline 200ml, hydrochloric acid sorbitine 10mg, methylene 10ml, stopped blood sensitivity 2ml, vitamin K1 5mg, intravenous drop; metronidazole 100ml, intravenous infusion; Virus high free serum 5ml, subcutaneous injection.
On January 29, the body temperature was 38.2 ° C, the blood was reduced. Treatment: 0.9% sodium chloride injection 100ml, 5% sodium hydrogencarbonate injection 10ml, intravenous drip; Linger’s fluid and 5% glucose biological saline 200ml, vitamin C 1G, Coenzyme A50 international unit, triphosphate adenosine 50mg, intravenous drop Note; vitamin K1 10mg, subcutaneous injection; anti-virus-free virus is high, blood, subcutaneous injection. Strengthen the care, feeding the right amount of royal low fat, easy digestive prescription, 1 hour every 4 hours.
On January 30, the body temperature was 38.6 ° C, the spirit improved, can live freely, take the initiative to find water, and blood is also reduced. Treatment: 200ml of Lindgra, vitamin C 1G, Coenzyme A50 international unit, triphosphate adenosine 50mg, intravenous drip; full nutrient liquid 100ml, intravenous drip; anti-virus high free serum 5ml, subcutaneous injection; pet fragrance 1 bag, 3 to 4 times a day; 0.5g of spermitrate 0.5g, oral, 1 hour every 24 hours.
On January 31, the body temperature was 38.4 ° C, diarrhea alleviation, blood loss, and spiritual improvement. Treatment: 0.9% sodium chloride injection 100ml, dog immunoglobulin 5mL, intravenous drip; 5% glucose injection 100ml, 10% calcium gluconate injection 6ml, potassium chloride injection 1ml, intravenous drip.
February 1On the day, the body temperature was 38.1 ° C, and continued to adjust the following drugs. 1 polyzyme tablet, oral, 1 hour every 12 hours; 1 prednisone, oral, 1 hour every 12 hours; 1 metronidazole, oral administration, 1 hour every 24 hours; Oral, every 8 hours; vitamin B12 1mg, subcutaneous injection; 1 ~ 3G, oral, 1 hour every 8 hours.
February 7, the disease was cured. Continue to fure dog food with warm water.

[1] Hou Jiafa. Small animal diseases. Beijing: China Agricultural Press, 2002
[2] Wang Chunhua, Wang Yunhai. Causes of impermunity failure of dog vaccine and corresponding Epidemic Prevention Countermeasures. Heilongjiang Animal Husbandry, 2003, 2: 24 ~ 25
[3] Chen Yuku. Dog Cat Internal Medicine. Beijing: China Agricultural Press. 2006
[4] Liu Zhongjie, Xu Jianqin. Zhongyuan Medicine, Third Edition. Beijing: China Agricultural Press, 2003
[5] Liang Bin. Chinese and Western Medicine combined with anti-virus disease. Chinese Virgin Medicine Journal, 2004, 3: 30 ~ 31
[6] Hu Yuanliang. Veterinary Press Manual, Second Edition. Beijing: China Agricultural Press, 2005
[7] Yin Yanjun. Chinese medicine dog treated dog fine viral enteritis test. China Animal Quarantine, 2002, 19 (3): 27 ~ 28
[8] Hu Yuanliang. Practical Animal Acupuncture Manual. Beijing: China Agricultural Press, 2003

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