Diagnosis and Prevention of Rabbit Salmonella – Raising Rabbit Forum – China Animal Husbandry Website – A useful animal husbandry website
This disease is a disease that is mainly caused by sepsis and acute death, and is accompanied by sepsis and acute deaths of Salmonella. The incidence and mortality rate of young rabbit and pregnant female rabbit are the highest.
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Salmonella Typltimurium and Salmonella Enteridis is Gram-negative, short-rod (2-4μm × 0.5 μm), has a weighted flage, and often bacteria, does not form a sprout. The bacteria is an aeronal oxygen and anaerobic anaerobic, which can grow well on a particular medium that does not add special growth factors, can be used as a single carbon source. Bacillus generally produces gas, no hydrolysis of urea, no fermentation lactose. The colonies are rounded, smooth, and humid in ordinary medium, which is translucent. Concentrated turbidity in the broth. The bacterium has selective utilization capabilities for disodium salts, so use these compounds as a systolic medium, and a small number of Salmonella can be separated from a highly contaminated specimen. In order to isolate the Sandenella, a variety of special formulations have been designed and selective medium. The most commonly used predecessor is bright green, McCona agar and bismuth sulfite agar. The optimal growth temperature of this bacillia is 370c, but at 43. C can also grow well, which is often used to reduce the indicators of miscellaneous dandes when they are separated from the bacteria in the specimens of severe pollution. Salmonella has three antigens, ie O (bacteria), H (flagelife) and VI (toxic) antigen. The specificity of the O antigen depends on the lipopolysaccharide structure and composition of the cell membrane; H antigen is constituted by the O antigen, which is composed of protein, unheathes heat; VI antigen is present on a typhoid sterile bacteria. The above antigen can be used in the identification of this bacterium.
Medyl bacterium resistance, in the dry environment, more than one month, often used disinfectant, such as carbonic acid and to Suer solution can be takenThe clock kills the bacteria.
Epidemiology from feces to the most important way to spread the rabbit Salmonella, such bacteria can cause disease to many kinds of animals, which are more complicated in certain animal groups.
The rabbit is more susceptible to Salmonella in the old rabbit. Since the bacteria is parasitic bacteria in the vertebrate intestines, when unsanitary, crowd, bad weather, childbirth, pregnancy, parasitic disease, transportation, viral infection, etc., can induce the Salmonella.
The feed is often contaminated due to mixed feed protein additives. In addition, wild rodents and flies are also the spread of this disease.
From the perspective of morbidity, intestinal diseases are more common, there can also occur in sepsis or bacteremia, which involves other systems to cause systemic diseases. There are three stages in the occurrence of Salmonella. Then, the bacterium is settled in the small intestine and the colon, which is in the normal closses in the normal case, which can produce volatile organic acid to develop Salmonella growth, and the normal bacteria of the intestine Salmonella can also be attached to the surface of the intestine. Those factors and antibiotics that can destroy normal bacteria, the lack of diet and moisture have greatly increased the susceptibility of the host on intestinal and septic Salmonella, and in addition, in particular the small intestine, it can also increase Salmonella. Settlement, and a lot of breeding. The Salmonella has entered the epithelial cell through the brush-shaped interface, and the bacteria reproduces and infects adjacent cells or transferred into the inherent layer to continue reproduction. At this time, the local lymphocytes are swallowed or restricted, and the intrusion of neutrophils is accompanied by neutrophils. Finally, the intrusion of Salmonella has caused inflammatory reactions and releases prostaglandin to activate adenosine cyclase, thereby causing the cell fluid outside to overflow, rapidly developing into an intestinal inflammation, which is characterized by a wide range of neutral cell infiltration in the center of the fluff. Acute ingastitis and colitis appeared. The occurrence of sepaging Salmonella, appears to be related to endotoxin released by the bacteria, and the endotoxin activity of Salmonella is present in the cell wall of lipopolysaccharides. Endotoxin causes a host fever, mucosal hemorrhage, and white blood cell reducing followed, while platelet decreases, hepatic sugar is exhausted and causes long-term hypoglycemia and shock or cause animal death.
In addition to the sudden death of individual cases, animals are generally diarrhea, high temperature Dani, anorexia, and spiritual. Filler flows from the uterus and vagina discharge, Vaginal mucosal edema, congestion, pregnant rabbit often aborted and cause death. After abortion, the rehabilitation rabbit will not be prone to pregnancy.
The lesional change is different from the course of disease. Suddenly died, the pathological changes of sepsis, most internal organs congestion and bleeding spots, chest, abdominal cavity, have a slurry or fibrous exudate; the liver, the spleen appears necrosis lesion, the lymphatic soda of the intestinal wall surface Some necrosis occurs. Occaible viscosity, bleeding, bleeding, mucous membrane edema, and a large amount of cellulose and white blood cell infiltration. Enteric lymph nodes also have congestive and edema lesions. Pregnant female rabbits or female rabbits that have been aborted, epqi endogenic, uterus, ulcer.
Diagnosis of the disease is mainly based on the test results of bacteria and serology. In acute cases, bacteria can be isolated from the serum, and bacteria can also be isolated from the liver, spleen, lymph nodes (especially mesenteric lymph nodes). In cases of enteritis and uterine inflammation can be isolated from the vaginal or uterine secretion to the bacteria.
Fresh materials of feces or other organ secretions of chronic or macrobial cases are inoculated in sodium sodium sulfate or sodium selenate, and after 37 ° C for 8-12 h, then inoculate in SS Or McCan selection medium. The separated bacteria were diagnosed with a biochemical reaction. In addition, the antigen can be used to diagnose the antigen with the serum of the rabbit to perform slide agglutination reactions.
Prevention of this disease mainly prevents the contact of the verandic rabbit and the source of infection. Once this is discovered, the treatment or elimination of the patients should be detected immediately, and the rabbit cage and the needle should be thoroughly disinfected, and the rabbit can be carried out by agglutination, and the positive person is preferably eliminated, facing the negative rabbit, can apply this place to separate Salmonella is made into a dead seedlings for preventing injection to control the epidemic of this disease.
Currently, many Salmonella strains have had a resistance to a variety of antibiotics, which seriously reduces the effectiveness of antibacterial therapy. Therefore, it is necessary to use antibiotics to be cautious. If the antibiotic antibiotics are used, it will destroy the settlement, which can provide protective strength of the host, so that the micro-state system is damaged, resulting in the proliferation of Salmonella. It causes sepsis by a blood circulation system.
When the bunny is bacterium or septic, the injection of chloramphenicol, gentamicin and trimethylsulfadineThe agent is effective for systemic Salmonella disease.
Original article, author：xinran，If reprinted，Please indicate the source：http://www.badpet.org/diagnosis-and-prevention-of-rabbit-salmonella-raising-rabbit-forum-china-animal-husbandry-website-a-useful-animal-husbandry-website/