Intestinal barrier – bird illness prevention and control – China Animal Husbandry Website – A useful animal husbandry website

The intestines are a congenital barrier that maintains environmental balance and obstructive bacteria and toxins in the intestine. The intestinal barrier includes a mechanical barrier, a chemical barrier, a microbial barrier, and an immune barrier. 6.jpg

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2020-6-16 17:26 Upload

Mechanical barrier is also called physical barriers, and its physiological structure is based on mucosal epithelials, intrinsic layers and mucosal muscle layers. Intestinal epithelial cells are tightly arranged in cell connections, and the connection between cells is composed of tightly linked, adhesive joints, and bridge, which can effectively block bacteria, viruses and endotoxin.

The chemical barrier consists of a bacterial substance secreted by the mucus, digestive fluid and normal bacteria secreted by intestinal epithelial cells. The intestinal mucosa has a large amount of cup-like cells, and the cup-like cell secretes mucus, and the dry liquid layer is translucent, continuously distributed in the surface of the intestinal mucosa, competes with the intestinal epithelial cell binding site, hinders the binding of bacteria to intestinal epithelium. The intestinal antibacterial substances mainly have bile, viscous polysaccharides, lysozymes and glycoproteins. Gastric acid is acidic, can kill most of the bacteria enters the oral cavity, and the acidic environment can protect the intestinal exemption from the pathogen infection. Bile and small intestinal fluid secreted by the liver also have certain inhibitory effects on pathogens. The intestinal flora main includes mucosa flora and intestinal flora, the mucosa flora is mainly based on bifidobacteria and lactic acid bacteria, and the intestinal psion is mostly E. coli and intestinal solid, they are adhered to the intestinal mucosa On, a multi-level intestinal microbial barrier is formed. Under normal circumstances, the number of intestinal microbes is relatively constant. The relative balance of microbial flora is stable, but feed, disease, immunization, stress, etc. may affect the number, activity or displacement of the intestinal flora, resulting in a patch balance disorder.
The intestinal mucosal immunization barrier is mainly composed of intestinal correlation lymphocyte tissue (GALT) and dispersion immune cells. Intestinal related lymphatic tissues include epithelial lymphade, inherent laminar lymphocytes and intestinal lymph nodes. In the intestinal mucosal epithelial cell, the inherent layer, and the mucosa under the mucosa, a large amount of lymphoid tissue and cells are distributed in the environments, viruses, toxins and other antigen stimulating the intestinal mucosa to produce an immune response, and the intestinal mucosal immune system can identify the antigen in the body, Generate body fluid immunity and cellular immunity, effectively cleaned against the original, and has the disease of the pathogenic microbial invasion.Anti-allergic reaction, inhibiting the function of immune response.

This topic was approved by 29625248 at 2020-6-17 09:19

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