Repair course | Talk about the prevention of false rabies (worth collecting) – Pig School Hall – China Animal Husbandry Website – A useful animal husbandry website

Pseudo-raw fang virus in the pathogenic classification of herpes virus, is a DNA virus, and it is very difficult to clinically. Pseudohadia is an acute infectious disease with a variety of livestock and wildlife fever, scuten (except for pigs) and cerebrosphenesis. This disease can happen in four seasons, but in winter and spring and the peak season, it is often a sow house in the peak of childbirth, and the nest is about 100%. The pathogenesis is mainly in the 15-year-old piglets, the initial age is 4 days old, the incidence of 98%, the mortality rate is 85%. As the age is growing, the mortality rate can be reduced, and the adult pigs are slightly sick, but very little death. The sow is more than a passage or subclinical infection, rarely die.

Pig is the only host you know, other livestock such as ruminants, cats and dogs often infected in natural circumstances. Many wild animals, ruminants and carnings, and wild rodents.
PRV infection

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Note that in the infection of all these animals, there is a fatal course of death. First, epidemiological characteristics and transmission pathway

Temporary season:

Winter spring season conversion and production in the middle of the month


Recessive Pour Pig

Introduced positive pig

Other poisonous animals (mice)
pigs are the only natural host of pseudohavisia, which is harmful to them. Can cause abortion in pregnant sows, dead and fetal dry bodies. The primary piglets cause neurological symptoms, moving disorders, paralysis, failure, and death rate of 100%. The adult pigs are more hidden infections, but can cause respiratory symptoms.

1, infectious sources: sick pigs, poison pigs and poisonous rats are the main infectious sources of this disease, the virus mainly eliminates the nasal separation, saliva, milk and urine of sick pigs, some Pattern pigs sustainable detoxification one year.

2, propagation route: The spread route is mainly direct or indirectly in contactInfection can also be infected by respiratory mucosa, damaged skin and ingredients. Pregnant sow infection This disease can be invaded by fetus by placenta, and there is a virus in a 1 week of lactate sow. It can last for 3 to 5 days. At this time, piglets can infect this disease due to breastfeeding.
3, latency: The latency of the disease is generally 3 to 5 days.
Second, clinical symptoms

1, the disease piglets were originally red, closed, then the body temperature rose to 41 ° C ~ 41.5 ° C, the spirit is depressed, there is a lot of bubbles or out of saliva, some The sick pig vomiting or diarrhea, the content is yellow, the initial nerve disorder is mainly paralyzed. The most common is intermittent convulsions, epilepsy, corner bow, blind walking or turning circle, staying. There is almost 100% of piglets that have neurological symptoms, and the pigs tenderly develop or become a stiff pig.

2, 20 days old, piglets, pigs in pigs, small pigs, the body temperature rises above 41 ° C, breathing short, be tertometh, no shock or loss of appetite, otopic purple, incidence rate and The mortality is less than 15 years of age.

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2018-2-9 09:12 Upload The pigs around 3, April, only slight symptoms after the disease, there are few days of light heat, breathing difficult, nose juice, cough, spirit, loss of appetite, and pigs “dog Sitting “posture, sometimes vomiting and diarrhea.

4, sows sometimes have anorexia, constipation, tremor, seizures, visual disappearance or conjunctivitis, some sows are delayed or in advance, some have a dead tire, mum nail or abortion, produce piglets Heavy small decline, weakness of the weak tires 2-3, and the incidence of abortion is about 50%.

Pregnant mother pig clinical manifestation

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naked eye lesions:

sick pig brainHydrogens, cerebral edema, small cerebral hemorrhage liver, spleen swollen, white necrotic point (needle tip size)

kidney spot bleeding (needle tip size)

pneumonia, pulmonary edema

tonsils have necrosis ( Not common)

Face skin damage

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Liver and spleen necrosis

intestinal damage

Third, pseudohadia PR popular Latest changes

Non-immunized pigs will have typical pseudohadia symptoms

sow: large-scale dead tires, abortion, mummy, returning ratio

Growing fattening pig: performance For severe respiratory disease symptoms


High-risk, high mortality

High-fever, vomiting, pull yellow, yellow, yellow, yellow, yellow, wanted

Typical neurological symptoms

sow: will sparest the dead, abortion, mummy, there is a certain proportion of sows return

Growth fattening pig: severe respiratory disease symptoms


Low incidence, low mortality,

pull yellow raasant

Respiratory disease symptoms

Occasional neurological symptoms

4 Why still pseudo-rabies sporadic occurrence after using PR vaccine?
This should still be characterized from a pseudo crazy.
PR virus emissions and latent infections: through the breathing trail secretion, semen, abortion fetus, and fetal liquid. In the first 2 days to 10-14 days, sometimes until 19-20 days. Within 7 months after infection, the immunosuppression can last for a long time to 18 months, and it is detected in the trigeminal nerve and brain tissue. Therefore, once the pig is infected, the PR will be born for life, or periodically. Of course, the latent infection can be detected by PCR.
Anti-disease immunity characteristics

body fluid immunization: itself is not protected (Kit et al, 1994, BOERSMA et al. 1998). It can be detected 8 days after infection, the titer rises from 1: 2-1: 4 to 1: 128-1: 512 and maintained for a few weeks. However, the neutralizing antibody does not prevent the virus from planting in nasopharyngeal

The mother antibody is 2-3 times the level of the sow blood antibody. Little pig blood antibody consistent with the level of primrose antibody within 1 day after childbirth. The half-life of the mother’s antibody approximately 10 days. All parent antibodies disappear at 16 weeks old.
(Note: Mother-induced mother-induced mother antibodies for mymia M. Hyo, only 3-4 weeks. The mother-of-parent antibody for fine virus (Parvovirus) can be maintained for 6 months. Breast-breast-proof antibodies for PRRS Maintain 8 weeks, but only 3 weeks.)

Local immunization

Cellular immunization: 7-14 days after infection, it was produced and maintained until 170 days.
Pseudo Travel (PR) is placed: prevention of latent infection

PRV vaccination summary:

Inoculation of vaccines does not produce 100% protection

Pigs inoculated may still infection

Pigs that have been inoculated can also be onset

The inoculated pig can still discharge viruses

5. We have to vaccinate PR vaccination. Comprehensive understanding
Current PR vaccination is still the most cost effective measures.

Vaccination can:

1, reduce infection

2, reduce the degree of infection of pigs, shorten the PR disease

3, reduce viral generation time (4X)

4, reduce Late infection (1000X)

5, reducing the disease repeated episode

The key is to choose a relatively excellent vaccine in the market.

First select the PR live vaccine, you must choose the GE (GI) gene lack vaccine, as it can distinguish infected pigs and immune pigs, while choosing a safe gene lack vaccine, only safety of each old pig, for others Animals are also safe.
PR inactivated seedling immunization is not complete, as:

1, PR inactivation is only humoral immunity, local immunity and cellular immunity are not strong

2, PR inactivation Muslims have no protection against pseudo-raw fantasy virus

3, immunized pigs can also be infected, onset

4, immunized pigs produce pigs can also be infected, onset

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Therefore, it is recommended that both vaccines can be used in combination. The characteristics of the living seedlings can quickly stimulate the immunization of cellular immunity and body fluids, and the immunity is maintained for a long time, and it is very good to prevent the death of piglets and sow. Can be used in general defenses; inactivating the seedlings can increase the milder antibody titer, which can be used in the tire immunity in the previous month.

Secondly selects a suitable inoculation method: muscle injection, nasal vaccination

Nasal vaccination:

Interference of the mother’s antibody
established cells as soon as possible Immunity

Reduces the emissions of positive pigs

Nasal vaccination cutting experiment attack catharsis

Viral emissions

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Arrange the appropriate immunization time

All must be immunized

3 – 4 times for sows every year

Pigs immunity is consistent

Turmunication in the first two times before entering the pig, the immunization interval is 3 weeks

small pig


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3 years ago Nasal immunization
4 – 5 weeks old nasal reinforced immunization

8-12 week old muscle vaccination

The author specially advocated 2-3 years old piglets early nasal nasal vaccination In this point, many of our pig farms have not been done.

Nasal immunity can avoid early infection of piglets


, the immunity maintenance time is short

When the PR is burst To be accurate diagnosis

All aged pigs must be vaccinated, or muscle injection muscle injection of pigs, 2 weeks, enhance immunization

6, current Comparison of several control and elimination of the PR method

1, PR treatment: there is no special treatment of drugs in this disease, and the infected pig can inject a pig-free rabies (pig farm can be prepared by elimination of mother pig blood) It has a significant effect on the piglet pigs, and simultaneously uses astragm polysaccharide Chinese medicine preparation. Emergency immunization is carried out for unpredictable threatening pigs.

2, preventive measures:

1 The disease should be prevention, the newly introduced pig should carry out strict quarantine, after introduction, observation, blood test, check GE positive pigs should inject a vaccine and can not be used.

2 pigs should regularly carry out voiced immunes, fattening pigs or weaning pigs should also be immunized from 2 to April. If they are immunized, the pig farm is only immunized with pigs, and the pig is infected with viruses. Detoxify, will detoxify Directly threaten a population.
3 Pig farms should perform regular stringent disinfection measures, it is recommended to use 2% sodium hydroxide (curated) solution or phenolic disinfectant.
4 In the pig farm, strict rodents should be carried out to eliminate the risk of murine poisoning dissemination.
3, more thorough measures – eliminate the cleansing:

Method: Cry – disinfection – vacuuming for more than 30 days, no pig.

Time: Choose in warmth Month.


Disadvantages: High cost.
4, Reproduction:

Method: Perform 10-21 days of break, then turn Advantage of “Cleaning Area”

: Blocking multiple infectious factors

Disadvantages: Piglet management is unfavorable.

Note: Mother sow should be non-toxic
5, on-site comparative economic measures – enhanced detection and phase out:

Method: Introducing a pig without infection with PR to replace a pig that has been infected with PR.

Advantages: small management Easy to implement.
6, management and immunization: similar to the detection and phase-out method

different points: no need to detect and eliminate the whole time, but in the elimination of serum-positive breeding pigs When serologizing negative breeds are replaced according to the normal update plan. Features: The time is long, and when all pigs in the finals are only negative, they can be considered without PR infection.
7. Implementing a PR Clear Schedule:

Serological examination of positive pigs can inject a gene lacking inactivating seedlings, and the immunization is enhanced at 4-6 weeks. Every 4 months will be injected once every 4 months, serum checking every six months.
Isolation of positive pigs infected with wild toar and phase out.

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Piglets have been used for GE antibody negatives at 100 days, and GE gene lacking seed seedlings at 100-10 days, in 130- 140 days of age in immunization, then immunization every half year, serological examination every half year. Time to eliminate wild infection of serum positive pigs. Wild poison infected serum positive pigs, injection of living seedlings or gene lacking seedlings, then injected once at 4-6 weeks, and finally raised as fattening pigs.

The pig removes the three intervals of 4-6 weeks of basic immunization, which should be injected once before breeding.

Each pig farm can choose one of the methods according to the characteristics of its own pig farms, but it must be an assessment of economic benefits before taking any measures.

Author: Shi Zengbin Source: pig professional managers

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