Where is the difference between bile acid and a carnitine? Let’s take a look at what the experts say? – Aquatic Forum – China Animal Husbandry Website – A useful animal husbandry website
The L-carnitine function is to transport the long chain fatty acid from the mitochondrial membrane to the film as a carrier, and β-oxidation is performed in the mitochondria, thereby generating energy, increasing the oxidation of the tissue on fatty acids. The main source of L-carnitine in the animal is 1 natural source: generally natural feed L-carnitine content is uneven, the content of plant feed is less (content of 10 mg / kg dry matter, generally no more than 50 mg / kg) The animal protein and milk products have more (content greater than 100 mg / kg). 2 in vivo synthesis. L-carnitine is synthesized by Lys, Met, three vitamins (niacin, ascorbic acid, VB6), divalent iron ions and enzymes, and can be directly absorbed or transferred after the participation of divalent iron ions and enzymes. Other tissue cells are supplied. In view of this, when using a carnitine product, it is necessary to choose from according to specific breeding varieties, specific breeding stages.
Compared with carnitine, the difference between bile acid is that the following four aspects: 1 bile acid can not only reduce fat accumulation, but also promote protein synthesis. Adding bile acids can reduce the expression of glutate dehydrogenase (GLDH) mRNA, increasing the expression of insulin-like growth factor 1 (IGF-1) mRNA in muscle, and the vitality of GLDH reflects the condition of protein decomposition in vivo. And IGF-1 can promote the synthesis of the protein.
2 Bile Acid promotes fat and disintegration. Bile acid can promote the digestive absorption of the body to the fat material in the feed by emulsifying, activating lipase, forming mixed chyloma, and the like. This is the carnitine. 3 Promote the mechanism of fat metabolism. As a signal molecule activates the liver and the napher X receptor (FXR) in the gastrointestinal tract, activating FXR can directly increase the expression and secretion of fibrous cell growth factor 21 (FGF21), and the increase in expression of FGF21 can reduce the liver. The content of triglycerides, additionally, FXR can also induce small identical metaderic molecular (SHP) gene expression, SHP reduces the expression of steroid adjustment element binding protein 1c (SREBP-1C) gene, then inhibits fat synthesis, lowering the liver Medium triglyceride content.
4 Bile Acids In vivo, the liver culture is carried out, and the role of the intestinal chemical barrier is used as the intestinal chemical barrier. IntestineThe bile acid in the inner bile acid can prevent it from absorbing the portal vein from the intestinal toxin, and endotoxin can also be broken down into non-toxic subunits or form a micromolymer, so bile acid can reduce endotoxin to the intestine, The harm of liver and even the whole fish. In addition to removing endotoxins, bile acids can also promote a large amount of thin bile with a large amount of thinning, excluding mold toxins, heavy metals and antibiotics, reducing these substances to the liver damage. This is also the carnitine.
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The article is from the official website of Shandong Longxuan. Longchang bile acid, carnitine
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